The generic name of Asendin is amoxapine. It works by aiding the balance of neurotransmitters in the brain. This is because the effects of amoxapine are similar to that of major tranquilizers.
Composition of Asendin
The chemical formula of asendin C17H16ClN3O with a molar mass of 313.781 g/mol. Asendin is a tricyclic antidepressant. Amoxapine is the N-demethylated metabolic substance of loxapine. The notable brand names of asendin include: defanyl, demolox, amoxapine and asendis.
Uses of Asendin
This medicine is used to cure major depressive disorder. Treating depression may help to enhance your mood as well as health and permits you to live your life in an enjoyable manner. Amoxapine is used to cure panic (anxiety) disorders and bipolar disorders.
How to Use Asendin
Asendin should be taken orally with/without food, once or more every day. Amoxapine can be initiated at a low dose for less side-effects and then gradually increasing the dosage according to the compatibility with the body. It is advised to consume the medicine during bedtime to avoid daytime drowsiness.
Side-Effects of Asendin
Drowsiness, problems while urinating, constipation, weakness, blurred vision, changes in weight, dry mouth, dizziness may occur as the body takes time to adjust. Notify the consultant promptly if any of these symptoms worsen or persist for long. Following are some rare but worsening side-effects:
- Mood/Mental changes
- Numbness of feet/hand
- Severe constipation/vomiting
- Ringing in the ears
- Increase in Prolactin level
- Extreme head ache
- Abdominal pain
- Jaw pain
- Irregular heart beat
- Chest/left arm pain
- Eye pain/redness/swelling
- Changes in vision
- Slurred speech
- Feeling weak on one side of the body
Sometimes this medication may cause tardive dyskinesia. In some conditions, this may be permanent. If any uncontrolled/uncertain movements of tongue, face, arms, mouth or legs are observed, then immediately consult your doctor. In some rare conditions it causes neuroleptic malignant syndrome with the indications of muscle stiffness, profuse sweating, fever, irregular heartbeat and severe confusion.
Contraindications of Asendin
It is not recommended for those who are allergic to tricyclic antidepressant. This medication may consist of some inactive substances which may be responsible for allergic reactions. The medical history should be revealed to the doctor, especially of: breathing problems (COPD, Asthma), blood problems (e.g. thrombocytopenia, agranulocytosis), intestinal issues (ileus, chronic constipation), kidney problems, heart diseases, liver issues and family history of mood/mental conditions (psychosis or bipolar disorder), urinating problems (enlarged prostate, retention of urine), history of neuroleptic malignant syndrome, suicide. The drug can also make you sensitive to sun rays.
Asendin in Pregnancy
This medicine should be avoided during pregnancy until it's really urgent. Mothers who had its intake during pregnancy may give birth to babies with problems like deep sleep, tremors, urinating difficulty and seizures. The drug enters the breast milk and may cause undesirable troubles on a nursing baby.
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