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Coumadin

COUMADIN

Coumadin (Warfarin) is used for treating or preventing blood clots that may occur because of a certain type of abnormal heartbeat or heart valve replacement.

Coumadin

The generic name used for this medication is Warfarin. It is referred as an anticoagulant or blood thinner. It is used for the treatment of blood clots occurring in pulmonary embolism or deep vein thrombosis. It can also be used for preventing strokes that might be common among people having artificial heart valves, valvular heart disease, or atrial fibrillation. It can also be used in orthopaedic surgery or ST-segment elevation myocardial infarction (STEMI), though not frequently.

Patients who have used this medication have reported several side effects among which bleeding is the most common one. Some of the less commonly observed ones may include purple toes syndrome and tissue damage. It will be discussed in detail further in the article.

There are several drugs and dietary factors that have chances of interfering with this medication to reduce its effectiveness. To reverse the effects of this drug, fresh frozen plasma, prothrombin complex concentrate, and Vitamin K1 or phytonadione can be used.

This medication was first used for commercial purposes in the year 1948 in the form of rat poison. In the year 1958, it was officially approved for medicinal purposes in the United States. It is also listed in the World Health Organization’s List of Essential Medicines to be effective and safe. The generic form of the medication is also available in the market.

Uses of Coumadin

As discussed earlier, this medication is used for treating blood clots that might occur in pulmonary embolus-PE and deep vein thrombosis-DVT. It can also be used for preventing the occurrence of blood clots in the body. Harmful blood clots can result in heart attack and stokes, hence preventing them can reduce their chance of occurring. Factors that are responsible for increasing the chances of developing blood clots are heart valve replacement, surgeries, recent heart attack, irregular heart rhythm, etc.

Side effects of Coumadin

It is natural that one might experience certain adverse effects along with the use of Coumadin. Watch out for these side effects and contact the doctor in case of emergency. Some of the common side effects are:

  • Headache
  • Paralysis
  • Chest discomfort or pain
  • Bleeding gums
  • Coughing up blood
  • Nosebleeds
  • Difficulty with swallowing or breathing
  • Bloody stools
  • Increased vaginal bleeding or menstrual flow
  • Unexplained swelling
  • Unusual weakness or tiredness
  • Dark brown or red urine
  • Diarrhoea
  • Purple or blue toes
  • Clay-coloured stools
  • Jaw, back, or arm pain
  • Irregular or fast breathing
  • Loss of appetite

Contraindications of Coumadin

Some conditions, if present in the patient, would not allow the use of this medication as it can result in harmful interferences. Some of these conditions are:

  • Spinal tap
  • Allergic reaction to Coumarin Analogues
  • Anaemia
  • Eye surgery
  • Inadequate Vitamin K

Pregnancy and Coumadin

Coumadin has been assigned the pregnancy category D and X in Australia and United States. Hence, this medication is not allowed to pregnant women.

Mode of Ingestion

Coumadin can be given intravenously or through the mouth to the patient.

Sometime patient's blood become too much thick and flow of the fluid become improper then in this way many of the diseases can attack on a person. Many medicines are available in market to treat this health problem. Coumadin is one of them and it is used for the similar way because thick blood may cause some sort of heart strokes and heart attack. In this problem there is a possibility of arteries disruption because of the clotting of the blood. In some of the precaution, it is recommended not to use this medicine if patient had bleeding problem in the stool or urine, heart infection, disorder of the bleeding in stomach, any brain upcoming surgery etc. it is mandatory to use this medicine on time otherwise its effectiveness decreased and moreover it is not recommended during pregnancy. Patient needs to be checking the blood test on to check the clotting time period while using Coumadin drug. Blood thinning for more than the extent may be harmful and it may change into life threatening problem because blood starts to come out from body's pore. In such situation immediately contact to the doctor or if you are having coughing, vomiting or bleeding. This medicine may creates problem for patient in such conditions as bleeding in stomach or intestine, bleeding in stool, hemophilia, or recent injury in brain, head or aneurysm. Sometime bleeding problem increased if patient had cancer, any history of bleeding, severe illness or age more than 65 years, liver problem or heart disease. Take a regular INR test of the blood which will determine that how much medicine is working effectively. It is very important to left the use of Coumadin before any sort of surgery because it is a blood thinner and in surgery situation it is very difficult to stop the thin blood and there are too many chances that blood will be wasted.

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