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Trusopt

TRUSOPT

Trusopt is a carbonic anhydrase inhibitor indicated in the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.

Trusopt

Trusopt is an anhydrase carbonic inhibitor. The generic name of Trusopt is Dorzolamide. It is used against glaucoma and helps in decreasing the formation of aqueous humour. It is a topical ophthalmic found in the form of solution. It belongs to the pregnancy category C and is usually administered in the form of eye drops.

Composition of Trusopt

The active ingredient of Trusopt is Dorzolamide (dorzolamide hydrochloride). The inactive ingredients present in the eye drop solution are as follows:

  • Benzalkonium chloride (as a preservative)
  • Sodium hydroxide
  • Sodium citrate dehydrate
  • Mannitol
  • Hydroxyethyl cellulose

Uses of Trusopt

This medication is widely used for treating high pressure present in the eye that is commonly caused by glaucoma (the open angle-type) or any other types of eye diseases (such as ocular hypertension). Reducing the high pressure can help in the prevention of blindness. The amount of fluid inside the eye is decreased with the help of this medication. The class of drugs Trusopt belongs to is carbonic anhydrase inhibitors.

Side-effects of Trusopt

Side-effects are adjacent to any medication or drug available. Some of these side-effects are discussed below:

  • Swelling, itching, redness or other sign of the eyelid or eye irritation
  • Discomfort, stinging or burning when medicine is applied
  • Excessive tearing
  • Burning, itching or dry eyes
  • Discharge from the eyes
  • Blurred vision
  • Skin rash
  • Blood in the urine
  • Vomiting or nausea
  • Pain in the abdomen, back or side
  • Diarrhoea
  • Flashes of light
  • Itching skin
  • Chills
  • Cough
  • Change in vision
  • Muscle or joint pain
  • Hives or welts
  • Noisy breathing
  • Tightness in the chest
  • Redness in the skin
  • Large, hive-like swelling on the face, eyelids, lips, throat, feet, legs, tongue or sex organs
  • Unusual tiredness or weakness
  • Sore throat
  • Floaters in vision
  • Difficult or laboured breathing
  • Dryness, flaking, burning, crusting or blistering of the skin
  • Seizures
  • Trembling
  • Weakness and heaviness of the legs
  • Muscle cramps or pain
  • Confusion
  • Irregular heartbeat
  • Pain, tingling, weakness or numbness in the hands or feet
  • Bitter taste
  • Headache
  • Increased sensitivity of the eyes to sunlight
  • Eyelid reactions
  • Difficulty seeing at night
  • Changes in colour vision
  • Bloody nose
  • Dizziness
  • Dry mouth
  • Scaling of the skin
  • Difficulty in focusing the eyes
  • Lack or loss of strength
  • Change in distance vision

Contraindications of Trusopt

Many medical conditions do not allow individuals to use Trusopt for treatment as it is harmful for their conditions. Hence, the doctor must make sure that the patient does not suffer from any of the following:

  • Allergic reaction to Carbonic Anhydrase Inhibitors
  • Severe Renal Impairment

Trusopt and Pregnancy

There has been evidence of teratogenic effects when given maternotoxic doses to animal subjects. It has been assigned to the pregnancy category C by the FDA. Therefore, it should only be given to a pregnant woman if the potential risks are not greater than the uses.

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