Browse all drugs:
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Efudex

EFUDEX

Efudex cream (fluorouracil) are topical preparations containing the fluorinated pyrimidine 5-fluorouracil, an antineoplastic antimetabolite.

Efudex

The brand name of Florouracil is Efudex. It is used to treat pre cancerous or cancerous conditions where the cells multiple rapidly or any skin growths that result due to exposure of the sun. Florouracil belongs to the family of anti metabolites.

Efudex cream is an antineoplastic.

MECHANISM OF ACTION (MOA)

Florouracil (5 FU) is a thymidylate synthase inhibitor. Inhibiting the action of enzyme stops the production of the pyrimidine thymidine. Thymidine is a nucleoside which is needed for the DNA replication. 5 FU decreases the d-TMP resulting in the cell death of the quickly dividing cancerous cells through thymineless cell death.

Uses of Efudex

It is used to treat:

1) Precancerous conditions

2) Cancerous conditions

3) Solar Keratoses

4) Actinic keratosis

5) Basal cell carcinoma (BCC)

6) Bowen's disease

7) Ocular surface squamous neoplasia

Some non cancerous conditions like

1) Genital warts

2) Psoriasis

3) Porokeratosis

Dosage and Administration

For solar keratosis

Apply the Efudex cream twice daily on the lesions. It should be enough to cover the lesion but don't overdo it. The usual duration of treatment is 2 to 4 weeks. But please continue the treatment until the inflammatory stage changes into erosion stage.

For BCC

Apply sufficient amount of cream twice daily to the lesions. The treatment should be continued to atleast three to six weeks. Please continue the treatment until every lesion has been obliterated.

As Efudex is in cream form it is applied to the lesions and we see the lesion respond a certain way it goes from erythema then vesiculation followed by desquamation then erosion and lastly re-epithelialization.

Efudex should not be applied with bare hands. Please use applicator or gloves for applying.

Side-Effects of Efudex

Common side-effects

1) Redness

2) Swelling

3) Burning sensation

4) Skin rash

5) Tenderness

6) Itching

7) Oozing

8) Scaling

9) Darkening of skin

10) Lacimation

11) Erosions

12) Pruritus

13) Hyperpigmentation

14) Blistering

15) Telangiectasia

16) Urticaria

17) Bullous pemphigoid

18) Abdominal pain

19) Vomiting

20) Bloody diarrhoea

21) Neutropenia

22) Inflammation of stomach, esophagus and small intestine

23) Insomnia

24) Stomatitis

25) Corneal reactions

26) Conjunctivitis

27) Thrombocytopenia

Precautions and Warning

Before using this product please give full personal and family history to your doctor of any diseases or allergies. As some inactive ingredient may cause harmful effect. Always apply sunscreen before going out in direct sun and please remember never to apply sunscreen other creams on Efudex. Please maintain a gap of 2 hour before applying any other cream or moisturiser.

Pregnancy and Breast-Feeding

During pregnancy this cream should not be used as it is harmful for the unborn baby .If applied to the mucus membrane during pregnancy it causes cleft lip in the infant. Please consult your doctor before taking this medicine.

It is not known if this medicine gets mixed with the breat milk or not but due to potential toxic effect it has been avoided during nursing.

Drug Interaction

Some drugs if interacts with other drugs may change the course of the medicine used. Therefore please consult your physician before using any drugs while taking Efudex.

Tags: buy efudex online, generic fluorouracil, efudex 10g.
Similar Products

Epivir

150mg x 240 Tabs

Epivir

Epivir is used for treatment of HIV infection in combination with other medicines.

Rebetol

200mg x 120 Tabs

Rebetol

Rebetol is used for treatment of hepatitis C infection in certain patients when used in combination with interferon.

Symmetrel

100mg x 240 Tabs

Symmetrel

Symmetrel treats and prevents certain types of flu. It is also treats Parkinson disease and uncontrolled muscle movements caused by some medicines.

» buy efudex without prescription: visa & mastrecard accepted.

top page