Antabuse is the brand name for the medication Disulfiram. It is a prescription medication used to support the treatment of alcohol dependence. Drug is not a cure for alcoholism but is intended to deter individuals from consuming alcohol by causing unpleasant symptoms when alcohol is ingested.

Drug Name: Antabuse

Active Ingredient: Disulfiram

Antabuse tablets



Form: Tablet

Type: Generic

Prescription Required: Rx

Availability: In Stock

When a person takes Antabuse and then consumes alcohol, it interferes with the normal metabolism of alcohol in the body. This leads to the accumulation of a toxic substance called acetaldehyde. As a result, individuals experience a range of unpleasant physical and psychological symptoms, including flushing, nausea, vomiting, headache, rapid heartbeat, chest pain, dizziness, sweating, and anxiety.

The purpose of Antabuse is to create a strong negative reaction to alcohol consumption, acting as a deterrent to help individuals abstain from drinking. By associating alcohol consumption with unpleasant effects, Disulfiram aims to support individuals in their efforts to maintain sobriety.

It's essential to understand that Antabuse alone is not a complete treatment for alcoholism. It is typically used as part of a comprehensive treatment plan that may include counseling, support groups, and other interventions to address the underlying causes of alcohol dependence.

How to use

Here are general instructions on how to use Antabuse:

  1. Timing: Antabuse is typically taken once a day. It is important to take it regularly to maintain a consistent level of the medication in your body. You can take tablets with or without food, but it's recommended to take it at the same time each day to help establish a routine.
  2. Compliance: Take medicament exactly as prescribed. Do not take more or less than the prescribed dose, and do not stop taking it. Stopping Antabuse abruptly can lead to withdrawal symptoms and may compromise your treatment.
  3. Avoiding Alcohol: It is crucial to avoid all forms of alcohol while taking Antabuse. Consuming alcohol while on Disulfiram can lead to a severe reaction, including unpleasant symptoms such as flushing, nausea, vomiting, headache, and rapid heartbeat.
  4. Duration of Treatment: The duration of treatment with Antabuse will be determined based on your progress and individual needs. It is essential to continue taking medicine as prescribed, even if you no longer have cravings for alcohol, to maintain sobriety.


The dosage of Antabuse prescribed to you will depend on various factors, including your individual needs, medical condition, and response to the medication. The following information provides general guidelines:

  1. Starting Dose: The typical starting dose of Antabuse for adults is 500 mg once daily.
  2. Maintenance Dose: The usual maintenance dose of Antabuse ranges from 250 mg to 500 mg per day. This dose is typically continued as long as you are trying to abstain from alcohol.
  3. Duration of Treatment: The duration of Antabuse treatment varies depending on individual circumstances.
  4. Pediatric Dose: Drug is not typically recommended for use in children. If there is a specific need for a child to take Antabuse, the dosage and safety considerations will be determined by a pediatric specialist.
  5. Elderly or Debilitated Patients: In elderly individuals or patients with reduced liver or kidney function, the initial dosage may be lower to minimize the risk of side effects.

Side effects

Antabuse may cause certain side effects in some individuals. Here are some common side effects associated with this drug:

Common Side Effects:

  • Fatigue or drowsiness
  • Headache
  • Skin rash or acne
  • Metallic or garlic-like taste in the mouth
  • Changes in sexual function or desire
  • Dizziness or lightheadedness
  • Nervousness or anxiety
  • Impotence in men

Rare but Serious Side Effects:

Although less common, Antabuse may also cause more serious side effects. If you experience any of the following, seek medical attention immediately:

  • Severe allergic reactions, such as rash, itching, swelling, severe dizziness, or difficulty breathing
  • Severe stomach pain or nausea
  • Yellowing of the skin or eyes (jaundice)
  • Dark urine or pale stools
  • Unusual bleeding or bruising
  • Tingling or numbness in the hands or feet
  • Vision changes or eye pain

Alcohol Interaction: Antabuse is specifically designed to cause an unpleasant reaction when alcohol is consumed. If you drink alcohol while taking Disulfiram, you may experience symptoms such as flushing, nausea, vomiting, headache, rapid heartbeat, and dizziness.


To ensure the stability and effectiveness of Antabuse, it is important to store it properly. Here are general guidelines for storing:

  1. Temperature: Store medicine at room temperature, typically between 68°F (20°C) and 77°F (25°C).
  2. Avoid moisture and light: Keep pills in its original container with the lid tightly closed. Protect it from excessive moisture, and store it away from direct light.
  3. Keep out of reach of children: Store Antabuse in a secure location that is out of the reach of children and pets. It is essential to prevent accidental ingestion or misuse.
  4. Follow packaging instructions: Always refer to the specific storage instructions provided on the packaging or label of your medication. Some formulations may have specific storage requirements.
  5. Do not use expired medication: Check the expiration date on the packaging, and do not use Antabuse if it has expired. Expired medication may not be as effective or safe to use.


An overdose of Antabuse can be a serious medical emergency and requires immediate medical attention. If you suspect an overdose or have accidentally taken more than the prescribed dose of Antabuse, take the following steps:

  1. Contact emergency services: Call your local emergency hotline or go to the nearest emergency room immediately. Inform them that you believe you have overdosed on Antabuse.
  2. Medical observation and treatment: In the hospital, medical professionals will closely monitor your vital signs, perform necessary tests, and provide supportive care to stabilize your condition. They may administer certain medications or employ procedures to manage the overdose symptoms.

Symptoms of an Disulfiram overdose may include severe nausea, vomiting, dizziness, confusion, breathing difficulties, seizures, and loss of consciousness. Prompt medical intervention is crucial to minimize the potential complications associated with an overdose.

In case of an emergency or suspected overdose, always seek immediate medical assistance by contacting your local emergency services or going to the nearest emergency room.

Missed Doses

If you accidentally miss a dose of Antabuse, here are some general guidelines to follow:

  1. Take the missed dose as soon as you remember: If you realize you missed a dose and it is not too close to the time for your next scheduled dose, take the missed dose as soon as possible. However, if it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule.
  2. Do not double the dose: Do not take a double dose to make up for the missed one. Taking more than the prescribed amount of Antabuse can increase the risk of side effects and complications.
  3. Follow your regular dosing schedule: Continue taking Antabuse as prescribed, following the usual dosing schedule. It is important to maintain a consistent level of the medication in your body to support your treatment plan.
  4. Avoid alcohol consumption: Remember that Antabuse is specifically designed to cause an unpleasant reaction when alcohol is consumed. Even if you miss a dose, it is essential to continue abstaining from alcohol completely to prevent any adverse effects.

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