Combivent is a medication that combines two active ingredients: ipratropium bromide and albuterol sulfate. It is commonly used in the treatment of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.

Drug Name: Combivent

Active Ingredient: Ipratropium bromide & Albuterol

Combivent inhalers



Form: Inhaler

Type: Generic

Prescription Required: Rx

Availability: In Stock

Ipratropium bromide is an anticholinergic bronchodilator that helps to relax and widen the airways in the lungs, making it easier to breathe. Albuterol sulfate is a short-acting beta-agonist bronchodilator that works by relaxing the muscles in the airways and increasing airflow to the lungs.

Combivent is usually available in the form of an inhalation aerosol, which is used with a metered-dose inhaler (MDI) or a Respimat inhaler. It is intended for inhalation into the lungs.

Please note that Combivent may be available in different formulations or under different brand names in various countries.

How to use

Using Combivent with a Metered-Dose Inhaler (MDI):

  1. Shake the inhaler: Shake the inhaler well before each use to ensure proper mixing of the medication.
  2. Prepare the inhaler: If it's your first time using the inhaler or if you haven't used it for a while, you may need to prime it. Follow the instructions provided to prime the inhaler before using it.
  3. Breathe out: Exhale fully to empty your lungs.
  4. Position the inhaler: Hold the inhaler upright with your thumb on the base and your index and middle fingers on the top of the canister.
  5. Seal your lips: Close your lips around the mouthpiece to form a tight seal.
  6. Inhale the medication: Start breathing in slowly and deeply through your mouth while pressing down firmly on the canister to release the medication. Continue to breathe in as deeply as you can.
  7. Hold your breath: After inhaling, remove the inhaler from your mouth and hold your breath for about 10 seconds, or as long as comfortable.
  8. Breathe out slowly: Exhale slowly away from the inhaler.
  9. Wait before the next dose: If a second dose is required, wait for the recommended time interval before repeating the steps.

Using Combivent with a Respimat Inhaler:

  1. Prepare the inhaler: Insert the cartridge into the inhaler and twist it until it clicks into place.
  2. Prime the inhaler: For the first use or if it hasn't been used for more than 3 days, hold the inhaler upright and point it away from your face. Press the dose-release button to release a test spray. Repeat this process until a visible spray is observed.
  3. Breathe out: Exhale fully to empty your lungs.
  4. Position the inhaler: Hold the inhaler in a level, horizontal position with your thumb on the base and your index and middle fingers on the sides of the inhaler.
  5. Inhale the medication: Place the mouthpiece between your lips and form a tight seal. While pressing the dose-release button, breathe in slowly and deeply.
  6. Hold your breath: After inhaling, remove the inhaler from your mouth and hold your breath for about 10 seconds, or as long as comfortable.
  7. Breathe out slowly: Exhale slowly away from the inhaler.
  8. Recap the inhaler: Replace the cap on the inhaler after each use.


The dosage of Combivent (ipratropium bromide and albuterol sulfate) may vary depending on the specific formulation, strength, and individual patient factors. The following dosage information is a general guideline:

Combivent Metered-Dose Inhaler (MDI):

  • The usual recommended dose for adults is 1 to 2 inhalations (puffs) every 4 to 6 hours, as needed for relief of symptoms.
  • The maximum daily dose should not exceed 12 inhalations in a 24-hour period.

Combivent Respimat Inhaler:

  • The usual recommended dose for adults is 1 inhalation (spray) 4 times a day.
  • The maximum daily dose should not exceed 6 inhalations in a 24-hour period.

Side effects

Combivent may cause side effects in some individuals. Common side effects may include:

  1. Dry mouth or throat
  2. Cough
  3. Headache
  4. Dizziness
  5. Nausea
  6. Upset stomach
  7. Tremor (shaking)
  8. Nervousness or anxiety
  9. Blurred vision
  10. Palpitations (rapid or irregular heartbeat)
  11. Throat irritation
  12. Taste changes

These are not all the possible side effects of Combivent. Some individuals may experience other side effects. If you notice any unusual or persistent side effects while using this medication, it is important to seek medical attention.

Severe allergic reactions to Combivent are rare but possible. Seek immediate medical help if you experience symptoms such as rash, itching, swelling (especially of the face, tongue, or throat), severe dizziness, or difficulty breathing.


To properly store Combivent, follow these guidelines:

  1. Keep Combivent in its original packaging: Store the medication in the original container provided by the manufacturer. This helps to protect it from light and moisture.
  2. Store at room temperature: Keep drug at a controlled room temperature between 20°C to 25°C (68°F to 77°F).
  3. Protect from moisture: Avoid exposing Combivent to excessive moisture, such as storing it in the bathroom. Moisture can degrade the medication and reduce its effectiveness.
  4. Keep away from heat: Avoid storing Combivent near direct heat sources, such as radiators or stoves.
  5. Do not freeze: Do not freeze Combivent. Freezing can alter the medication and make it ineffective.
  6. Keep out of reach of children and pets: Store inhalers in a secure location that is out of the reach of children and pets. Accidental ingestion or misuse can be harmful.
  7. Check expiration date: Before using Combivent, always check the expiration date on the packaging. Do not use the medication if it has expired.


An overdose of Combivent can be serious and requires immediate medical attention. If you suspect an overdose or have accidentally taken more than the prescribed dose of this drug, contact emergency services or your local poison control center right away. Here are some signs and symptoms of overdose:

  1. Increased heart rate: You may experience a rapid or irregular heartbeat, known as tachycardia.
  2. Chest pain: You may feel chest discomfort or pain.
  3. Tremors: Shaking or trembling of the hands, fingers, or other parts of the body can occur.
  4. Nervousness or anxiety: You may feel excessively anxious or agitated.
  5. Dizziness or lightheadedness: A sense of feeling unsteady or faint may occur.
  6. Excessive sweating: You may experience profuse sweating.
  7. Headache: A severe or persistent headache can occur.
  8. Difficulty breathing: Breathing may become difficult or labored.
  9. Seizures: In rare cases, seizures may occur.

It is important to seek immediate medical attention if you suspect an overdose. Be prepared to provide information about the quantity of Combivent taken and the time of ingestion.

In case of an overdose, do not try to induce vomiting unless instructed to do so by medical professionals.

Please note that this is not an exhaustive list of overdose symptoms, and individual responses may vary. Always follow the prescribed dosage of Combivent and seek medical advice if you have any concerns.

Missed Doses

If you miss a dose of Combivent, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

Here are some important points to keep in mind regarding missed doses of Combivent:

  1. Follow your prescribed schedule: It is important to adhere to the prescribed dosing schedule for Combivent. This helps maintain steady levels of the medication in your system and ensures optimal control of your symptoms.
  2. Do not take extra doses: Taking more than the prescribed dose of Combivent can increase the risk of side effects without providing additional benefit. Avoid doubling up on doses to make up for a missed one.
  3. Set reminders: If you have trouble remembering to take your doses, consider setting reminders or alarms to help you stay on track with your medication schedule.

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