Coversyl is a medication that contains the active ingredient perindopril. It belongs to a class of drugs known as angiotensin-converting enzyme (ACE) inhibitors. Medicine is primarily used to treat hypertension (high blood pressure) and certain cardiovascular conditions.

Drug Name: Coversyl

Active Ingredient: Perindopril

Coversyl tablets



Form: Tablet

Type: Generic

Prescription Required: Rx

Availability: In Stock

The main function of Coversyl is to block the action of an enzyme called ACE, which is involved in the production of a substance called angiotensin II. Angiotensin II is a hormone that can cause blood vessels to constrict, leading to increased blood pressure. By inhibiting ACE, Perindopril helps relax and widen the blood vessels, allowing blood to flow more easily and reducing blood pressure.

In addition to hypertension, Coversyl may also be prescribed for other cardiovascular conditions, such as congestive heart failure or after a heart attack, to improve heart function and reduce the risk of future cardiovascular events.

Medicament is available in different strengths and formulations, including tablets and extended-release tablets. The dosage and duration of treatment will vary depending on the specific condition being treated and the individual patient's response to the medication.

How to use

Here are some general guidelines for using Coversyl:

  1. Timing: Take tablets once a day, preferably in the morning, with or without food. It is important to take it at the same time each day to maintain a consistent level of the medication in your body.
  2. Compliance: Take Coversyl regularly and as prescribed. Skipping doses or not taking it consistently may affect its effectiveness in controlling your blood pressure. If you accidentally miss a dose, take it as soon as you remember, but if it is close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.
  3. Interactions: Coversyl may interact with certain medications, including nonsteroidal anti-inflammatory drugs (NSAIDs), potassium-sparing diuretics, or lithium.
  4. Lifestyle changes: In addition to taking Coversyl, it is important to make lifestyle modifications to help manage your blood pressure. This may include maintaining a healthy diet low in sodium, regular exercise, weight management, limiting alcohol consumption, and quitting smoking.
  5. Safety measures: Be cautious when standing up or changing positions, as Perindopril can sometimes cause dizziness. If you experience dizziness, sit or lie down until the symptoms subside. It is also important to avoid excessive heat and dehydration, as Perindopril can affect your body's response to these conditions.
  6. Medication management: Store Coversyl at room temperature, away from moisture and heat. Keep it out of reach of children and dispose of any expired or unused medication properly.


The dosage of Coversyl may vary depending on the specific condition being treated and individual patient factors. The following are some general dosage guidelines:

  1. Hypertension (high blood pressure): The usual starting dose for most patients is 4 milligrams (mg) once daily. The maintenance dose typically ranges from 4 mg to 8 mg per day. In some cases, a higher dose may be required.
  2. Heart failure: The starting dose for heart failure patients is usually 2 mg per day. You may increase the dosage gradually to a maximum of 8 mg per day, based on your tolerance and response to the medication.
  3. Post-heart attack (myocardial infarction): The recommended dose for post-heart attack patients is 8 mg per day, starting within 3 to 7 days after the event.
  4. Elderly patients or patients with kidney problems: For elderly patients or those with impaired kidney function, a lower starting dose may be prescribed.

Coversyl is available in different strengths, including 2 mg, 4 mg, and 8 mg tablets.

Side effects

Coversyl may cause certain side effects, although not everyone will experience them. It's important to be aware of potential side effects while using this medication. Common side effects may include:

  1. Cough: A persistent dry cough is a common side effect of ACE inhibitors like Perindopril.
  2. Dizziness or lightheadedness: Some individuals may experience dizziness or lightheadedness, especially when standing up quickly. It is advisable to rise slowly from a seated or lying position to minimize this side effect.
  3. Fatigue or weakness: Coversyl can sometimes cause feelings of fatigue or weakness.
  4. Headache: Headaches may occur as a common side effect.
  5. Nausea or stomach discomfort: Some individuals may experience mild gastrointestinal symptoms such as nausea, stomach pain, or indigestion. Taking Coversyl with food or dividing the daily dosage into smaller doses may help alleviate these symptoms.
  6. Skin rash: In rare cases, Coversyl may cause a skin rash or itching. If you notice any skin changes or allergic reactions, seek medical attention promptly.
  7. Hypotension (low blood pressure): Coversyl's blood pressure-lowering effects can sometimes cause a drop in blood pressure, leading to symptoms like dizziness or fainting.
  8. Other side effects: Less frequently, Perindopril may cause other side effects such as muscle cramps, taste disturbances, kidney problems, or changes in blood test results.

It's important to note that this is not an exhaustive list of side effects, and others may occur. Additionally, some side effects of Coversyl may be more severe and require immediate medical attention. If you experience severe allergic reactions, swelling of the face or throat, difficulty breathing, or symptoms of a heart attack, seek emergency medical help.


To ensure the stability and effectiveness of Coversyl, it is important to store the medication properly. Here are some guidelines for storing:

  1. Temperature: Store Coversyl at room temperature, typically between 20°C to 25°C (68°F to 77°F). Avoid exposing the medication to excessive heat or cold. Keep it away from direct sunlight and sources of heat, such as radiators or stoves.
  2. Moisture: Protect Coversyl from moisture. Store the medication in its original packaging or a tightly closed container to prevent exposure to humidity or dampness. Avoid storing it in the bathroom or near sinks.
  3. Childproof container: Keep tablets in a childproof container or in a secure location out of the reach of children and pets. Accidental ingestion of Coversyl can be harmful, so it is important to take precautions to prevent access to the medication.
  4. Medication disposal: If you have expired or unused tablets, it is important to dispose of them properly. Do not flush the medication down the toilet or pour it into drains unless instructed to do so.

Remember, proper storage helps maintain the integrity and effectiveness of the medication, ensuring its safe and optimal use.


An overdose of Perindopril can be dangerous and requires immediate medical attention. If you suspect an overdose or have taken more than the prescribed dosage of Coversyl, take the following steps:

  1. Seek emergency medical help: Contact your local emergency services or go to the nearest emergency room right away. Inform them about the situation and that you suspect an overdose of Coversyl.
  2. Do not induce vomiting: Do not try to induce vomiting. Vomiting may not be effective in removing the medication from your system and can potentially cause harm.
  3. Be prepared with information: Provide as much information as possible to the medical professionals regarding the quantity of Coversyl taken, the time of ingestion, and any other relevant details. This information will assist them in determining the appropriate course of treatment.
  4. Medical treatment: In cases of Coversyl overdose, treatment typically involves supportive measures to manage the symptoms and stabilize your condition. This may include monitoring vital signs, providing fluids, administering activated charcoal, or implementing other medical interventions as deemed necessary.

It is important to remember that an overdose of Coversyl can have serious consequences. The specific symptoms and severity of an overdose can vary depending on factors such as the amount ingested, individual tolerance, and other medications or substances taken concurrently.

Prompt intervention can help mitigate the potential risks associated with an overdose and ensure your well-being.

Missed Doses

If you miss a dose of Coversyl, it is important to take the necessary steps to manage the situation. Here are some general guidelines for dealing with missed doses:

  1. Take the missed dose as soon as you remember: If you realize you missed a dose of Coversyl, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one.
  2. Do not take extra doses: Taking more than the prescribed dosage of Coversyl can increase the risk of side effects and may be harmful. Stick to your regular dosing schedule and do not take additional doses to compensate for missed ones.
  3. Maintain regular dosing: After a missed dose, continue taking Perindopril according to your regular dosing schedule. It is important to take the medication consistently to maintain its effectiveness in managing your blood pressure or other conditions.
  4. Set reminders: To help avoid missed doses in the future, consider setting reminders or alarms to prompt you to take your medication at the same time each day. You can use phone alarms, medication reminder apps, or other tools to help you remember.

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