Buy Efudex Cream (fluorouracil) Online
The brand name of Florouracil is Efudex. It is used to treat pre cancerous or cancerous conditions where the cells multiple rapidly or any skin growths that result due to exposure of the sun. Florouracil belongs to the family of anti metabolites.
Efudex cream is an antineoplastic.
MECHANISM OF ACTION (MOA)
Florouracil (5 FU) is a thymidylate synthase inhibitor. Inhibiting the action of enzyme stops the production of the pyrimidine thymidine. Thymidine is a nucleoside which is needed for the DNA replication. 5 FU decreases the d-TMP resulting in the cell death of the quickly dividing cancerous cells through thymineless cell death.
Uses of Efudex
It is used to treat:
- Precancerous conditions
- Cancerous conditions
- Solar Keratoses
- Actinic keratosis
- Basal cell carcinoma (BCC)
- Bowen's disease
- Ocular surface squamous neoplasia
Some non cancerous conditions like
- Genital warts
Dosage and Administration
For solar keratosis
Apply the Efudex cream twice daily on the lesions. It should be enough to cover the lesion but don't overdo it. The usual duration of treatment is 2 to 4 weeks. But please continue the treatment until the inflammatory stage changes into erosion stage.
Apply sufficient amount of cream twice daily to the lesions. The treatment should be continued to atleast three to six weeks. Please continue the treatment until every lesion has been obliterated.
As Efudex is in cream form it is applied to the lesions and we see the lesion respond a certain way it goes from erythema then vesiculation followed by desquamation then erosion and lastly re-epithelialization.
Efudex should not be applied with bare hands. Please use applicator or gloves for applying.
Side-Effects of Efudex
- Burning sensation
- Skin rash
- Darkening of skin
- Bullous pemphigoid
- Abdominal pain
- Bloody diarrhoea
- Inflammation of stomach, esophagus and small intestine
- Corneal reactions
Precautions and Warning
Before using this product please give full personal and family history to your doctor of any diseases or allergies. As some inactive ingredient may cause harmful effect. Always apply sunscreen before going out in direct sun and please remember never to apply sunscreen other creams on Efudex. Please maintain a gap of 2 hour before applying any other cream or moisturiser.
Pregnancy and Breast-Feeding
During pregnancy this cream should not be used as it is harmful for the unborn baby .If applied to the mucus membrane during pregnancy it causes cleft lip in the infant. Please consult your doctor before taking this medicine.
It is not known if this medicine gets mixed with the breat milk or not but due to potential toxic effect it has been avoided during nursing.
Some drugs if interacts with other drugs may change the course of the medicine used. Therefore please consult your physician before using any drugs while taking Efudex.
150mg x 240 Tabs
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