Glucotrol is the brand name for the medication glipizide, which belongs to a class of drugs called sulfonylureas. It is an oral antidiabetic medication used to treat type 2 diabetes mellitus.

Drug Name: Glucotrol

Active Ingredient: Glipizide

Glucotrol tablets



Form: Tablet

Type: Generic

Prescription Required: Rx

Availability: In Stock

Glucotrol works by stimulating the release of insulin from the pancreas and increasing the sensitivity of cells to insulin, which helps lower blood sugar levels in individuals with type 2 diabetes.

It is important to note that Glipizide is not used to treat type 1 diabetes or diabetic ketoacidosis. It is typically prescribed alongside a proper diet and exercise regimen to help manage blood sugar levels in individuals with type 2 diabetes.

How to use

Here are some general guidelines for using Glucotrol:

  1. Take as directed: Take drug exactly as prescribed. Follow the recommended dosage and dosing schedule.
  2. Timing of administration: Medicine is usually taken orally once daily, typically with breakfast or the first main meal of the day.
  3. Swallow the tablets whole: Take the tablets with a full glass of water. Do not crush, break, or chew the tablets.
  4. Follow dietary instructions: It is important to follow a balanced diet and meal plan. Certain foods, especially those high in carbohydrates, can affect your blood sugar levels, and your doctor may provide specific dietary instructions to help manage your condition.
  5. Do not skip doses: Take Glucotrol consistently and do not skip doses. If you accidentally miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.


The dosage of Glucotrol may vary depending on individual factors such as the severity of your diabetes, your response to the medication, and other medical conditions you may have. Here are some general dosage guidelines:

  1. Starting dose: The usual starting dose of Glucotrol is 5 mg once daily, taken with breakfast or the first main meal of the day.
  2. Maintenance dose: The maintenance dose typically ranges from 5 mg to 20 mg per day, divided into two or more doses.
  3. Maximum dose: The maximum recommended daily dose of Glucotrol is usually 40 mg, but this may vary depending on individual circumstances. Higher doses may increase the risk of side effects.
  4. Renal or hepatic impairment: If you have kidney or liver problems, you may adjust the dosage of Glipizide or choose an alternative treatment option. This is because impaired kidney or liver function can affect the metabolism and elimination of the medication from your body.

Side effects

Glucotrol may cause certain side effects in some individuals. While not everyone experiences these side effects, it is important to be aware of them. Common side effects include:

  1. Hypoglycemia: Glucotrol lowers blood sugar levels, and sometimes this can lead to hypoglycemia (low blood sugar). Symptoms may include sweating, shaking, dizziness, hunger, headache, blurred vision, and difficulty concentrating. It is important to monitor your blood sugar levels regularly and be cautious of the signs of low blood sugar. Always carry a source of fast-acting glucose, such as glucose tablets or sugar, in case of hypoglycemia.
  2. Gastrointestinal effects: Some people may experience gastrointestinal side effects such as nausea, vomiting, diarrhea, or stomach upset. These symptoms are usually mild and transient.
  3. Weight gain: Glipizide may lead to weight gain in some individuals. It is important to maintain a healthy lifestyle, including a balanced diet and regular exercise, to manage your weight effectively.
  4. Allergic reactions: Although rare, allergic reactions to Glucotrol can occur. Seek immediate medical attention if you experience symptoms such as rash, itching, swelling, severe dizziness, or difficulty breathing.
  5. Skin reactions: Medicine has been associated with skin reactions, including rash, itching, and hives.
  6. Liver function changes: In rare cases, Glucotrol may affect liver function.
  7. Blood disorders: Drug can rarely cause blood disorders, such as changes in white blood cell count.


To properly store Glucotrol, it is important to follow these guidelines:

  1. Temperature: Store Glucotrol at room temperature, preferably below 25°C (77°F). Avoid exposing the medication to extreme heat or cold.
  2. Moisture: Keep the medication in a dry place, away from excessive moisture. Do not store it in the bathroom or near sinks.
  3. Light: Protect Medicine from direct sunlight and excessive light exposure. Store it in a dark place, such as a closed drawer or cabinet.
  4. Container: Keep Glucotrol in its original packaging or container. Ensure that the container is tightly closed to prevent moisture or air from entering.
  5. Accessibility: Store tablets out of the reach of children and pets. It is important to prevent accidental ingestion or misuse of the medication.
  6. Disposal: Follow proper disposal guidelines for medication. If you have expired or unused tablets, consult your pharmacist or local waste disposal authorities on how to safely dispose of them.

Remember to always check the expiration date of Glucotrol before use. If the medication has expired, do not use it and consult your pharmacist for a replacement.

Proper storage helps to maintain the effectiveness and safety of Glipizide. If you have any specific storage-related questions or concerns, it is best to consult your pharmacist for personalized advice.


An overdose of Glucotrol can have serious consequences and requires immediate medical attention. If you suspect an overdose or have taken more than the prescribed dose of Glucotrol, it is important to take the following steps:

  1. Contact emergency services: Call your local emergency helpline or go to the nearest emergency room immediately. Inform them that you have taken an overdose of Glucotrol.
  2. Do not induce vomiting: Vomiting may not effectively remove the medication from your system and can potentially cause more harm.
  3. Medical evaluation and support: In the emergency room, healthcare professionals will assess your condition, monitor vital signs, and provide appropriate treatment. They may administer activated charcoal or use other methods to reduce the absorption of Glucotrol in your body.
  4. Monitoring and treatment: You may require close monitoring of your blood sugar levels, as Glipizide overdose can cause severe hypoglycemia (low blood sugar). Intravenous fluids, glucose, or other medications may be administered to stabilize your blood sugar levels and manage symptoms.
  5. Supportive care: Additional supportive care may be provided as needed, depending on the specific symptoms and complications that arise from the overdose. This may include monitoring of vital signs, respiratory support, or other medical interventions.

It is important to seek medical help immediately in case of a Glucotrol overdose. Even if you are unsure about the severity of the situation, it is better to err on the side of caution and seek prompt medical attention.

Missed Doses

If you miss a dose of Glucotrol, here are some general guidelines to follow:

  1. Take the missed dose as soon as you remember: If you realize that you have missed a dose and it is not close to the time for your next scheduled dose, take the missed dose as soon as possible. However, if it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule.
  2. Do not double the dose: Do not take a double dose of Glucotrol to make up for the missed dose. Taking more than the prescribed amount can increase the risk of low blood sugar (hypoglycemia).
  3. Follow your regular dosing schedule: Continue taking Glipizide according to your prescribed dosing schedule. It is important to maintain consistency in taking the medication to effectively control your blood sugar levels.
  4. Monitor your blood sugar levels: If you miss a dose of Glucotrol, monitor your blood sugar levels closely. If you experience symptoms of low blood sugar, such as sweating, shaking, dizziness, or hunger, take appropriate measures to raise your blood sugar levels, such as consuming a source of fast-acting glucose, like glucose tablets or sugar.

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