Inspra is the brand name for the medication Eplerenone. It belongs to a class of drugs called mineralocorticoid receptor antagonists. Medicine is primarily used to treat high blood pressure (hypertension) and to improve survival rates in patients who have experienced heart failure after a heart attack.

Drug Name: Inspra

Active Ingredient: Eplerenone

Inspra tablets



Form: Tablet

Type: Generic

Prescription Required: Rx

Availability: In Stock

Inspra is typically prescribed as part of a comprehensive treatment plan that may include lifestyle changes and other medications.

How to use

Here are general guidelines for using Inspra:

  1. Take with or without food: Medicine can be taken with or without food. It is important to be consistent in how you take it, either always with food or always without food, to ensure consistent absorption.
  2. Swallow whole: Take the tablet whole with a glass of water. Do not crush, break, or chew the tablet.
  3. Follow a regular schedule: Try to take Inspra at the same time each day to maintain a consistent level of the medication in your body. Setting a reminder or incorporating it into your daily routine can help you remember to take it regularly.
  4. Do not double dose: If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
  5. Keep taking as prescribed: Even if you start feeling better, continue taking Inspra as prescribed. Stopping the medication abruptly can lead to a sudden increase in blood pressure or worsened heart failure symptoms.


The following are general dosage guidelines for Inspra:

  1. Hypertension: The usual starting dose for treating high blood pressure is 50 mg of Inspra once daily. The maximum recommended daily dose is 50 mg.
  2. Heart failure after a heart attack: The usual starting dose for heart failure patients following a heart attack is 25 mg of Inspra once daily. The maximum recommended daily dose is 50 mg.
  3. Liver impairment: If you have mild to moderate liver impairment, your doctor may start you on a lower dose of Inspra to minimize the risk of side effects.
  4. Elderly patients: In elderly patients, the starting dose and dose adjustments may be considered based on individual factors such as renal function and overall health status.

Side effects

Medicine may cause side effects in some individuals. While not everyone experiences side effects, it is important to be aware of potential adverse reactions. Common side effects can include:

  1. Dizziness or lightheadedness: You may feel dizzy or lightheaded, especially when standing up from a sitting or lying position. Taking precautionary measures such as getting up slowly can help minimize this effect.
  2. Headache: Some individuals may experience headaches while taking Inspra.
  3. Fatigue: Feeling tired or fatigued is another possible side effect.
  4. Diarrhea: Eplerenone may cause diarrhea in some individuals. It is important to stay hydrated.
  5. Increased potassium levels: Inspra can raise potassium levels in the blood, which may lead to symptoms such as muscle weakness, irregular heartbeat, or numbness/tingling.
  6. Allergic reactions: In rare cases, allergic reactions may occur, presenting symptoms like rash, itching, swelling, severe dizziness, or difficulty breathing. Seek immediate medical attention if you experience these symptoms.


When it comes to storing Inspra, it is important to follow the recommended guidelines to maintain the medication's effectiveness and ensure safety. Here are some general storage instructions:

  1. Temperature: Store medicine at room temperature, typically around 20-25°C (68-77°F).
  2. Avoid moisture and light: Keep the medication in its original container, tightly closed, and protect it from moisture and excessive light. Avoid storing it in the bathroom or near sinks where it can be exposed to moisture.
  3. Keep away from children and pets: Store Inspra in a safe and secure place out of the reach of children and pets. The medication should only be used by the individual it has been prescribed for.
  4. Do not transfer to other containers: Keep tablets in its original packaging and avoid transferring it to different containers. The original packaging is designed to provide proper protection and information about the medication.
  5. Check expiration date: Before taking Inspra, ensure that it has not expired. Do not use the medication if it is past the expiration date. Properly dispose of expired or unused medication as directed by your local regulations.


In case of an overdose of Eplerenone, it is crucial to seek immediate medical attention or contact your local poison control center. An overdose of Inspra can have serious consequences, and prompt medical intervention is necessary. Here are some important points to keep in mind:

  1. Symptoms of overdose: Overdosing on Inspra may lead to an excessive decrease in blood pressure, an increase in potassium levels (hyperkalemia), and other adverse effects. Symptoms may include dizziness, fainting, irregular heartbeat, muscle weakness, confusion, or numbness/tingling. However, the specific symptoms can vary from person to person.
  2. Do not induce vomiting: Do not induce vomiting unless directed to do so by medical professionals.
  3. Prompt medical attention: Call emergency services or go to the nearest emergency room immediately if an overdose is suspected. Provide them with information about the medication taken, the dosage, and the timing of the overdose.
  4. Bring the medication: Take the Inspra packaging or any remaining tablets with you to the hospital to assist medical professionals in understanding the situation and providing appropriate care.
  5. Supportive treatment: Treatment for an Inspra overdose will focus on managing symptoms and supporting vital functions. This may include measures to stabilize blood pressure, monitor potassium levels, and provide other necessary interventions.

Remember, an overdose of any medication can be dangerous. It is important to take medications as prescribed and to reach out for emergency medical assistance if an overdose is suspected.

Missed Doses

If you miss a dose of Inspra, follow these general guidelines:

  1. Take it as soon as you remember: If you remember within a few hours of the missed dose, take the missed dose as soon as possible. If it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.
  2. Maintain a regular schedule: To ensure the effectiveness of Inspra, try to take it at the same time each day. Setting a reminder or incorporating it into your daily routine can help you remember to take it consistently.
  3. Do not compensate with extra doses: It is important not to take extra doses of Inspra to make up for missed ones. Taking more than the prescribed amount can increase the risk of side effects without providing additional benefit.

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