Drug Name: Mestinon
Active Ingredient: Pyridostigmine
Availability: In Stock
By inhibiting the breakdown of acetylcholine, Mestinon helps to increase the levels of this neurotransmitter at the neuromuscular junction, which improves muscle strength and reduces fatigue in individuals with myasthenia gravis. It is typically prescribed as part of a comprehensive treatment plan that may also include other medications, lifestyle modifications, and sometimes surgical interventions.
Mestinon is available in various forms, including tablets, extended-release tablets, and syrup.
How to use
The dosage and administration guidelines may vary depending on your specific condition. Here are some general guidelines for using Mestinon:
- Read the medication guide: Start by carefully reading the medication guide that comes with the Mestinon prescription. It contains important information about the medication, including dosage instructions, potential side effects, and precautions.
- Timing of doses: Medicine is usually taken multiple times a day. Follow the prescribed schedule and try to take the medication at the same times each day to maintain consistent levels in your body.
- Take with or without food: Mestinon can be taken with or without food, but it is important to be consistent with your choice. If you decide to take it with food, try to take it around the same time with each meal.
- Swallow tablets with water: If you are taking tablets, swallow them whole with a full glass of water. Do not crush, chew, or break the tablets.
- Extended-release tablets: If you are prescribed Pyridostigmine extended-release tablets, they are designed to release the medication slowly over time. Do not crush, chew, or break these tablets, as it can interfere with their extended-release properties.
- Liquid formulation: If you are prescribed Mestinon syrup, use a measuring device (such as a dosing spoon or syringe) to ensure accurate measurement of the prescribed dose. Shake the bottle well before each use.
The dosage of Mestinon can vary depending on several factors, including the individual's condition, age, weight, and response to the medication. The following are general dosage guidelines:
- Adults: The typical starting dose is 60 mg to 120 mg, taken every 3 to 4 hours during the day. The total daily dose can range from 600 mg to 1,500 mg.
- Children: The dosage is usually based on the child's weight. The starting dose is typically 7 mg per kilogram of body weight, divided into smaller doses throughout the day.
Postoperative Urinary Retention:
- Adults: The usual dosage is 5 mg to 20 mg, taken orally once or twice daily as needed.
Reversal of Nondepolarizing Muscle Relaxants:
- Adults: The recommended dose is 10 mg to 25 mg, taken orally 2 to 3 times a day.
Mestinon may cause side effects in some individuals. Here are some common side effects:
- Gastrointestinal Disturbances: These may include nausea, vomiting, abdominal cramps, diarrhea, or increased saliva production. Taking Mestinon with food or adjusting the dosage may help manage these symptoms.
- Sweating and Increased Salivation: Some people may experience excessive sweating or increased saliva production while taking Mestinon. These effects are generally temporary and should improve with continued use.
- Muscle Cramps: Mestinon may cause muscle cramps, particularly in the early stages of treatment.
- Urination Changes: Pyridostigmine may affect urinary function, leading to increased frequency or urgency to urinate.
- Increased Heart Rate: Mestinon can occasionally cause an increase in heart rate. If you notice a rapid or irregular heartbeat, chest pain, or any other cardiovascular symptoms, seek medical attention promptly.
- Blood Pressure Changes: Medicine may affect blood pressure, leading to either increased or decreased blood pressure levels.
- Allergic Reactions: Although rare, allergic reactions to Mestinon can occur. If you experience symptoms such as rash, itching, swelling, dizziness, or difficulty breathing, seek immediate medical assistance.
It is essential to remember that these are not exhaustive lists of side effects. Some individuals may experience side effects not listed here. Additionally, the severity and frequency of side effects can vary from person to person.
Here are general guidelines for storing Mestinon:
- Temperature: Store tablets at room temperature, typically between 20°C to 25°C (68°F to 77°F). Avoid exposing it to extreme heat or cold.
- Moisture: Keep medicine in a dry place. Do not store it in a bathroom or any area with high humidity, as moisture can affect the stability of the medication.
- Light: Protect Mestinon from excessive light. Store it in its original packaging, which is designed to shield it from light exposure.
- Container: Keep tablets in its original container or blister pack until you are ready to use it. The packaging is designed to provide proper protection and labeling information.
- Childproofing: If you have children or pets at home, make sure to store Mestinon in a secure location that is out of their reach. Childproof caps on containers can provide an extra layer of safety.
- Medication Disposal: When disposing of Mestinon, follow the local regulations and guidelines for medication disposal. Do not flush it down the toilet or pour it down the drain unless specifically instructed to do so.
An overdose of Pyridostigmine can be potentially serious and requires immediate medical attention. If you suspect an overdose or have taken more than the prescribed dose, take the following steps:
- Seek Emergency Medical Assistance: Call your local emergency services or go to the nearest emergency room immediately. Inform them that you have taken an overdose of Mestinon.
- Do Not Induce Vomiting: Vomiting may worsen the situation or cause additional complications.
- Provide Information: When you seek medical help, provide accurate information about the medication you have taken, including the name, the dosage strength, and the amount ingested.
- Treatment Options: Treatment for Mestinon overdose may include measures to remove the medication from your body, supportive care to manage symptoms, and interventions to stabilize vital functions.
It is crucial to seek immediate medical assistance in case of a Mestinon overdose. Even if you are unsure whether an overdose has occurred, it is better to err on the side of caution and seek professional help.
If you miss a dose of Mestinon, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
It is important to maintain consistency in taking Mestinon to ensure a steady level of the medication in your body. However, if you frequently forget to take your doses or have trouble remembering, consider using reminders such as setting alarms, using medication reminder apps, or asking a family member or caregiver to assist you.