Nexium is the brand name for the medication esomeprazole. It belongs to a class of drugs called proton pump inhibitors (PPIs). Medicine is primarily used to treat conditions related to excessive stomach acid production, including gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome.

Drug Name: Nexium

Active Ingredient: Esomeprazole

Nexium capsules



Form: Capsule

Type: Generic

Prescription Required: Rx

Availability: In Stock

Nexium works by reducing the amount of acid produced in the stomach. It does this by blocking the action of proton pumps, which are responsible for the final step of acid secretion in the stomach lining. By decreasing stomach acid production, Medicine helps alleviate symptoms such as heartburn, acid reflux, and stomach ulcers.

Drug is available in various forms, including delayed-release capsules and oral suspensions.

How to use

Here are some general guidelines for using Nexium, but please note that your specific dosage and instructions may vary:

  1. Take Medicine at the same time each day: It is recommended to take Nexium at the same time every day to maintain consistent levels of the medication in your body. This will help ensure its effectiveness.
  2. Swallow the capsule whole: Take capsules with a glass of water. Swallow the capsule whole without crushing or chewing it. If you have difficulty swallowing, you may open the capsule and sprinkle the contents on a spoonful of applesauce. Swallow the mixture immediately without chewing.
  3. Take Nexium before meals: Nexium is usually taken before meals to maximize its effectiveness.
  4. Do not crush or split delayed-release capsules: Delayed-release capsules are designed to release the medication slowly. Do not crush or split the capsules.
  5. Do not take with other medications: To ensure optimal absorption, it is recommended to take Nexium at least one hour before or one hour after taking other medications.
  6. Complete the full course of treatment: It is important to continue taking Nexium for the full duration, even if your symptoms improve before completing the course. Stopping the medication prematurely may allow your symptoms to return.


The dosage of Nexium can vary depending on the specific condition being treated and individual patient factors. The information provided here is a general guideline, but it may not be applicable to everyone.

For the treatment of gastroesophageal reflux disease (GERD) and acid-related conditions, the usual recommended dosage of Nexium for adults is 20 to 40 mg once daily.

For the treatment of Helicobacter pylori (H. pylori) infection in combination with antibiotics, the usual recommended dosage of Nexium for adults is 20 mg or 40 mg twice daily, in combination with appropriate antibiotics.

For the prevention of peptic ulcers caused by nonsteroidal anti-inflammatory drugs (NSAIDs), the usual recommended dosage of Nexium for adults is 20 mg or 40 mg once daily.

For the treatment of Zollinger-Ellison syndrome and other conditions associated with excessive stomach acid production, the dosage of Nexium may be higher.

The dosage for children and adolescents may differ based on their age, weight, and specific condition.

Side effects

The following are potential side effects associated with the use of Nexium. Keep in mind that not everyone will experience these side effects, and their severity and frequency can vary:

  1. Headache: A common side effect of Nexium is a headache. It is usually mild and temporary.
  2. Nausea and vomiting: Some individuals may experience nausea or vomiting while taking this drug.
  3. Diarrhea or constipation: Medicine can occasionally cause changes in bowel habits, leading to diarrhea or constipation.
  4. Abdominal pain: Some individuals may experience abdominal pain or discomfort while taking Nexium.
  5. Flatulence (gas): Nexium may cause increased gas production or bloating in some individuals. This is usually temporary and subsides over time.
  6. Dry mouth: Dry mouth is a potential side effect of Esomeprazole. Sipping water throughout the day or using sugar-free gum or lozenges can help alleviate dryness.
  7. Dizziness: In rare cases, Drug may cause dizziness. If you experience dizziness that affects your daily activities, seek medical attention.
  8. Skin reactions: Some individuals may experience skin reactions such as rash, itching, or hives while taking Nexium. If you develop a severe rash or difficulty breathing, seek immediate medical attention.
  9. Vitamin B12 deficiency: Prolonged use of Nexium may lead to a decrease in vitamin B12 levels in some individuals. Regular monitoring and supplementation may be necessary, especially in patients on long-term therapy.
  10. Osteoporosis-related fractures: Prolonged use of high-dose Nexium or use of PPIs for extended periods may slightly increase the risk of fractures, particularly in the hip, wrist, or spine.


To properly store Nexium, please follow these guidelines:

  1. Store at room temperature: Keep capsules at a temperature between 68°F (20°C) and 77°F (25°C).
  2. Protect from moisture: Store the medication in a dry place. Keep the blister packs or bottles tightly closed to protect the tablets or capsules from moisture.
  3. Avoid extreme temperatures: Do not expose Esomeprazole to excessive heat or cold. Avoid storing it in areas such as the bathroom or near the kitchen sink where it may be exposed to moisture or temperature fluctuations.
  4. Keep out of reach of children and pets: Store Nexium in a secure location, out of sight and reach of children and pets. The medication should only be accessed and used by the intended individual under proper supervision.
  5. Follow specific instructions: If provided, follow any additional storage instructions on the packaging or information leaflet provided by the manufacturer or pharmacist.
  6. Check expiration date: Regularly check the expiration date on the packaging. Do not use Nexium if it has expired. Properly dispose of any expired medication following local guidelines.

It's important to note that these storage guidelines are general recommendations. Always refer to the specific instructions provided with your medication or consult your pharmacist if you have any doubts or concerns regarding the proper storage of Nexium. Following proper storage practices helps maintain the effectiveness and quality of the medication.


An overdose of Nexium can have serious consequences, and prompt medical intervention is crucial. Here's what you should do:

  1. Call emergency services or poison control center: Contact emergency services or your local poison control center right away. They can provide guidance on what steps to take and may advise you to seek immediate medical assistance.
  2. Provide information: Be prepared to provide information about the amount of Nexium ingested, the time of ingestion, and any symptoms you or the affected individual may be experiencing.
  3. Do not induce vomiting: Vomiting may not effectively remove the medication from the system and can potentially cause additional harm.
  4. Receive medical treatment: Upon seeking medical assistance, the healthcare team will assess the situation and provide appropriate treatment. They may administer activated charcoal to help prevent further absorption of the medication or employ other medical interventions based on the severity of the overdose.

It is crucial to remember that an overdose of Nexium can have serious health implications. Therefore, if you suspect an overdose or have accidentally taken more than the prescribed dose, do not delay seeking medical help.

Missed Doses

If you miss a dose of Nexium, here are some general guidelines to follow:

  1. Take the missed dose as soon as you remember: If you realize you have missed a dose and it is within a few hours of the scheduled time, take the missed dose as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.
  2. Do not double the dose: Do not take a double dose of Nexium to make up for the missed one. Taking more than the prescribed amount can increase the risk of side effects without providing additional benefit.
  3. Resume the regular dosing schedule: After taking the missed dose or skipping it, continue taking Nexium as prescribed. It is important to maintain a consistent dosing schedule for the medication to be effective in managing your condition.

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