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Questran

Questran

Questran is a brand name for the medication called Cholestyramine. It belongs to a class of drugs known as bile acid sequestrants. Medicine is primarily used to lower high levels of cholesterol in the blood. It works by binding to bile acids in the intestine, preventing their reabsorption and promoting their excretion from the body. This process leads to an increase in the elimination of cholesterol from the body, helping to reduce cholesterol levels in the blood.

Drug Name: Questran

Active Ingredient: Cholestyramine

Questran sachets

Dosage:

4mg

Form: Sachet

Type: Generic

Prescription Required: Rx

Availability: In Stock

In addition to its cholesterol-lowering effects, Questran may also be used in the treatment of certain types of diarrhea, particularly those associated with excess bile acids in the intestine.

Medicine is available in powder form for oral administration. It is usually mixed with water or other liquids before ingestion. The medication is typically taken once or twice daily.

It's important to note that Cholestyramine should be used as part of a comprehensive treatment plan that includes dietary modifications and lifestyle changes.

How to use

Here are general guidelines for using Questran:

  1. Prepare the Medication: Cholestyramine is available as a powder. Measure the prescribed amount of Questran powder using the scoop or measuring spoon provided.
  2. Mix with Liquid: Add the measured dose of Questran powder to a glass of water or other liquids, such as fruit juice or milk. Stir the mixture well until the powder is completely dissolved. It may take a few minutes for the powder to fully dissolve.
  3. Take the Medication: Drink the entire mixture of Questran and liquid. You may take it with or without food. Make sure to consume the full dose as prescribed.
  4. Timing with Other Medications: If you take other medications, it is important to take Questran at least 1 hour before or 4 hours after taking any other medication. This is because Questran can interfere with the absorption of other medications, reducing their effectiveness.
  5. Stay Hydrated: Ensure you drink plenty of fluids throughout the day while taking Questran. This helps prevent dehydration, as Cholestyramine can absorb water in the intestines and may lead to constipation if not enough fluids are consumed.

Dosage

The following are general guidelines for the dosage of Questran:

High Cholesterol:

  • The usual starting dose for adults is 4 grams (one packet or scoop) once or twice daily.
  • The maximum recommended daily dose is 24 grams (six packets or scoops) per day.

Diarrhea:

  • The dosage for diarrhea associated with excess bile acids may range from 4 to 8 grams (one to two packets or scoops) per day.

Children:

  • Pediatric dosages are typically lower than adult dosages and may need adjustment over time.

Remember to drink plenty of fluids while taking Cholestyramine to prevent dehydration and constipation. Be sure to take Questran at least 1 hour before or 4 hours after taking any other medications, as it can interfere with their absorption.

Side effects

Here are some common side effects associated with Questran:

Gastrointestinal Effects:

  • Constipation: Questran can slow down bowel movements, leading to constipation. Increasing fluid intake and dietary fiber can help alleviate this side effect.
  • Abdominal discomfort: Some individuals may experience bloating, stomach cramps, or flatulence (excessive gas).

Vitamin Deficiencies:

  • Malabsorption of fat-soluble vitamins: Questran can interfere with the absorption of fat-soluble vitamins (vitamins A, D, E, and K) and certain medications.

Other Possible Side Effects:

  • Nausea or vomiting: These symptoms may occur but are less common.
  • Allergic reactions: Although rare, some individuals may experience allergic reactions such as itching, rash, or hives.

It's important to note that this is not an exhaustive list of side effects, and other rare or severe side effects may occur.

Storage

To ensure the effectiveness and stability of Questran, it is important to store it properly. Here are some general guidelines for storing:

  1. Keep in a Cool, Dry Place: Store drug at room temperature, away from excessive heat, moisture, and direct sunlight.
  2. Protect from Moisture: Keep the medication in its original tightly closed container to protect it from moisture. Do not transfer the powder to another container.
  3. Avoid Extreme Temperatures: Do not store Questran in the refrigerator or freezer. Extreme temperatures can affect the stability of the medication.
  4. Keep Out of Reach of Children: Store Questran in a secure location, out of the reach of children and pets.
  5. Follow Specific Instructions: Always follow any specific storage instructions provided by the manufacturer or on the product packaging.

Overdose

If you suspect an overdose of Cholestyramine, it is important to seek immediate medical attention or contact your local poison control center. Overdosing on Questran can lead to an excessive binding of bile acids and may cause gastrointestinal symptoms and electrolyte imbalances.

Here are some signs and symptoms of an overdose that you should be aware of:

  1. Severe constipation or intestinal obstruction: Excessive use of Questran can lead to severe constipation, abdominal pain, and possible intestinal blockage.
  2. Electrolyte disturbances: Overdose of Cholestyramine may result in electrolyte imbalances, such as low potassium levels (hypokalemia).
  3. Nutritional deficiencies: Prolonged excessive use of Questran can interfere with the absorption of fat-soluble vitamins (vitamins A, D, E, and K) and essential nutrients.

If you or someone you know has taken an overdose of Questran, it is important to seek medical attention immediately. Call emergency services or your local poison control center for guidance on what steps to take. Be prepared to provide information about the medication and the amount ingested, if known.

Missed Doses

If you miss a dose of Questran, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.

It is important to try to take Questran consistently and at the same time(s) each day to maintain its effectiveness. However, if you occasionally forget to take a dose, it should not cause significant harm. Consistency in taking the medication is more important for long-term management rather than an occasional missed dose.

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