Sovaldi (Sofosbuvir) is a medicine used to treat chronic hepatitis C genotype 1, 2, 3, or 4 infection in adults and children under 18 years of age.

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It is a prescription medicine and is used for the treatment of chronic hepatitis C. It is an antiviral which prevents the hepatitis C virus from multiplying in our body. It is also known as Sofosbuvir and is used in a combination with other medicines. It should not be used alone. It is usually prescribed with ribavirin or daklinza. It was first introduced in the year 2013 and has a very high curing rate.

Composition of Sovaldi:

It is a nucleotide analog inhibitor of HCV NS5B polymerase. The molecular formula of sovaldi is C22H29FN3O9P and it has a molecular weight of 529.45. It is a white to off-white crystalline solid and is slightly soluble in water. Each tablet contains 400 mg of this medicine. The tablets have the following inactive elements in it magnesium stearate, mannitol, and microcrystalline cellulose. The sovaldi tablets are film-coated. The coating material of this medicine contains the following inactive constituent polyethylene glycol, talc, titanium dioxide, polyvinyl alcohol, and yellow iron oxide.

Uses of Sovaldi:

This medicine is used to treat hepatitis C in adults. At times this medicine is also used for patients who have HIV, liver transplant or liver cancer, however, this medicine is not a treatment for HIV.

Side- Effects of Sovaldi:

This medicine has its own side effects. In case you have any signs of allergies such as swelling of face, tongue, or throat, hives, or unable to breathe, get medical help immediately. Some of the common symptoms are headache, fatigue, nausea, insomnia, anemia, pruritus, asthenia, rash, chills, decreased appetite, illness with the symptoms of influenza, pyrexia, neutropenia, diarrhea, myalgia, blurred vision, pale skin, rapid heartbeat, trouble in concentrating, dry skin, muscle spasms and irritability. Some of the less common side effects of this medicine are pancytopenia, severe depression and suicidal tendencies.

Contraindications of Sovaldi:

Before you start taking this medicine, let your doctor know if you have any allergies to this medicine or to any other inactive ingredient of this medicine or any other allergies. This medicine is usually used in a combination with other medicines. One such medicine is Ribavirin. This medicine causes birth defects in an unborn baby, hence it is advised to not use this medicine if your partner is pregnant. Also, let the doctor know if you have liver problems or if you have had a liver transplant, if you are on dialysis or some kidney disease, HIV or if you are using any heart rhythm medicines. The doctor will advise at least 2 effective non-hormonal birth control medicines to prevent pregnancy while using this medicine.

Pregnancy and Sovaldi:

Scientific experiments have not confirmed yet if the medicine sovaldi can harm the child during pregnancy. Also, it is not known to pass into the breast milk or harm the nursing child.

Hepatitis - causes and treatments

The liver forms a very vital organ in our digestive system. It secretes several acids like the bile that is needed to digest food items. It also has several other functions as well like fighting infection, cleansing toxins and removing waste.

From that perspective, the liver′s functions are indispensable. Any damage to the organ will result in a whole disruption of bodily functions. Some of these disruptions are caused by several disorders and diseases like Hepatitis that is a common disease among men especially for those who work in comparatively poorer hygienic conditions. Feelings of jaundice and and a yellowing skin should be more than enough for you to visit the doctor.

Hepatitis - types and physiology

Hepatitis is a viral disease that affects the human liver. There are primarily 5 types of Hepatitis - Hepatitis A, hepatitis B and all the way till hepatitis E. Most commonly observed are hepatitis A, hepatitis B and hepatitis C. Most of them have common symptoms and causes as well as treatments and that we have written down below.

This disease affects how the liver functions, mostly stopping its normal functioning and giving it an inflamed look.

What causes hepatitis?

Causes for hepatitis are a long list. Some of its common causes can still be summarised:

  • Typhoid.
  • Excessive Alcohol intake.
  • Q fever.
  • Bacterial infections.
  • Contaminated or unhygienic food and water.
  • Unhygienic living conditions.
  • Herpes.
  • Tattoos.
  • Contaminated needles.
  • Poor sanitation.
  • Narcotic dependence.
  • Cirrhosis.
  • HIV.
  • Certain plant poisonings.
  • Several viruses like Marburg virus, Kawasaki virus, microsporidiosis.

Symptoms of hepatitis

Since there are five categories of hepatitis, listing down symptoms for each of them might result in a long list. However, certain common symptoms exist:

  • Fever.
  • Headache.
  • Flu-like signals.
  • Yellowing of the skin.
  • Jaundice.
  • Vomiting and nausea.
  • In some cases, haemorrhage.
  • Malaise.

However, not all hepatitis exhibit the same behaviour as listed above. Diseases like hepatitis C hardly exhibit any symptom at all until the disease reaches a very advanced stage. This leads to further complications like chronic hepatitis, cirrhosis, liver cancer and even death.


Hepatitis is usually diagnosed through the following tests:

  • Testing symptoms.
  • Physical examinations.
  • Blood tests.
  • Liver biopsy.
  • Imaging.
  • Serology.
  • Nucleic acid tests.


Hepatitis is treated through several medications:

  • Periodic visit to the gastroenterologist during infection.
  • Sovaldi.
  • Hepsera.
  • Interferon.
  • Telbivudine.
  • Tenovofir.
  • Baraclude.

Each of the hepatitis has its own medications, so ensure the doctor prescribes you the proper medicines. You can always confirm those on the internet.

Preventing hepatitis

Hepatitis is a viral disease that is caused due to unhygienic conditions or contact with contaminated food or water that contains the hepatitis virus. So, prevention points out towards hygienic conditions and proper food intake as well. Ensure that you eat vegetables and fruits that boost immunity and help fighting any infection.

Of course, there are other several practices like stopping alcohol, being attentive towards symptoms that can always prevent hepatitis from occurring and advancing into deadlier stages.

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