Zyprexa (olanzapine) is actually an antipsychotic medication which tends to affect the chemicals present in the brain. Zyprexa is also used in the treatment of the symptoms of psychotic circumstanceslike schizophrenia & bipolar disorder in adults & children who happen to be more than 13 years of age.
Composition of Zyprexa
Zyprexa which contains olanzapine as an active ingredient is an antipsychotic drug belonging to the thienobenzodiazepine class of medications. The molecular formula for Zyprexa is C17H20N4S with the molecular wt of 312.44. Typically, Olanzapine is a yellow coloured crystalline solid, insoluble in water.
Each tablet of Zyprexacontains olanzapine of strength 2.5 mg, 5 mg, 7.5 mg, 10 mg, 15 mg or 20 mg. Along with it, the inactive ingredients of Zyprexa include carnauba wax, crospovidone,microcrystalline cellulose, hypromellose, lactose, hydroxypropyl cellulose and magnesium stearate. Zyprexa tablets which are coated with a film are made up of titanium dioxide, FD& C Blue Number 2 Aluminum Lake (in case of 15 mg tablet) and Synthetic Red Iron Oxide (in case of 20 mg tablet). The 2.5 mg, 5 mg, 7.5mg & 10 mg tablets are usually imprinted with an edible ink which is made up of FD& C Blue Number 2 Aluminum Lake.
Zyprexa is also available in the form of orally disintegrating tablet in strengths of 5 mg, 10 mg, 15 mg or 20 mg. Along with this, it also contains inactive ingredients like gelatin, sodium methyl paraben,mannitol, sodium propyl paraben and aspartame.
Uses of Zyprexa
Zyprexa which contains olanzapine as an active ingredient is used for the treatment of certain mood/mental conditions like schizophrenia or bipolar disorder. It can also be used along with other medications for reducing depression or to decrease hallucinations. It also helps one think more positively and clearly about self, feel less agitated& be more active in everyday life.
Olanzapine belongs to atypical antipsychoticsclass of drugs whichworks by helping restore the equilibrium of certain kinds of natural substances in brain. This drug can also be used in treating nausea & vomiting which might be caused by chemotherapy.
Side effects of Zyprexa
In case of Zyprexa, the following are the severe side effects which one might experience after consumption of the medication-
- Difficulty in breathing;
- Swelling of the face, tongue, lips or throat
- Uncontrolled muscle movement of the face (frowning, tongue movement, chewing, lip smacking, blinking or some eye movement)
- trouble in speaking or swallowing
- swelling in the hands or the feet
- Confusion, hallucinations, unusual thoughts and/or behaviorof hurting self
- sudden weakness or the feeling of illness
- Fever, chills or sore throat
- cold or flu symptoms
- Signs of dehydration like feelingthirsty or hot
- Not being able to urinate
- heavy sweating
- hot or dry skin
- upper stomach pain
- itching or loss of appetite
- dark coloured urine
- clay colored stools
- Blurred vision
- Loss of weight
In case of Zyprexa, the following are the common side effects which one might experience after consumption of the medication-
- weight gain
- increased appetite
- headache, dizziness or drowsiness
- Feeling of tiredness or restlessness
- problems with memory or speech
- tremors or shaking
- changes in the personality
- dry mouth, or increase in the salivation
- stomach pain or constipation
- pain in the arms or the legs
Contraindications of Zyprexa
Zyprexa should not be taken by one, if he/she is:
- Allergic to olanzapine
- Has liver disease
- Has heart disease orlow or high blood pressure
- Has a history of low WBC count
- Has high cholesterol and triglycerides
- Has a history of heart attack or heart failures
- Has a history of stroke or breast cancer
- Has seizures or epilepsy
- Has diabetes
- Has an enlarged prostate
- Has difficulty urinating
- Has bowel problems
- Has narrow angle glaucoma
Pregnancy and Zyprexa
Zyprexa is an FDA pregnancy category C drug, which means how the drug will behave in case of pregnancy, is not known. Hence a doctor needs to be informed when one plans on getting pregnant or is pregnant. Zyprexa might pass into the breast milk and may cause some harm to the baby being nursed, and hence while breastfeeding a baby this medication needs to be avoided.
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