Parkinson`S Effect On The Gut
Parkinson`s disease is a health issue that affects the neurons in our body. It is also classified as a neurodegenerative disorder which affects the dopamine-producing neurons of the brain. This area is also termed substantia nigra. The signs of this disorder grow slowly over the years. The way the symptoms progress is different from people to people. It is mostly due to the diversity of the disease. This disease involves the malfunction and death of nerve cells in the brain. Studies have suggested that this disorder may start from the gut. There have been many pieces of evidence which have been supporting this claim. As per a new study, the protein in the nerve cells which are affected by this disorder can also be found in the cells which line the small intestine. This research was done in humans and other mammals as well.
These studies showed that the protein is first broken down in the gut and then it travels to the brain. It is there that it causes the symptoms of Parkinson`s disease. As of now it is affecting around 10 million people worldwide and is a progressive movement disorder. It is known that it affects more than 1 million in the United States alone as per the Parkinson's Disease Foundation.
Our brain contains a protein called alpha-synuclein in abundance. In the healthy body, the protein dissolves in the fluid within the cells, however, in people with Parkinson's Disease or PD the same protein folds abnormally. This then spreads through the nervous system and to the brain and is called prion. The prion is the infected protein and these protein molecules then stick to each other to form a clump which can further damage the neurons. In early 2005 in a research, it was found that the people with Parkinson's Disease had these clumps in their brains and also in their gut. In another study, it was found that people with ulcers and who underwent a surgery to have the base of the vagus nerve removed which actually connected the brain stem to the abdomen. The risk of Parkinson's Disease went down by 40 percent for such people compared to those who did not have the vagus nerve removed.
The only problem was that the researchers were unable to understand how the proteins affected in the gut could spread to the brain. The protein was found in the part of the gastrointestinal tract which is not open to the lumen. In the year 2015, the researchers were able to find a relation. It was found that the cell lining of the small intestine acted a lot like nerve cells. These cells were able to produce hormone as they were endocrine cells. These cells then branch out in the similar way that neurons are to communicate and pass on the information. This has given new hope to treat the Parkinson's Disease in people as new treatments can be created to prevent the abnormal protein cell formation.
Health Information Articles
- Carbs Causing Trouble for Patients Having Inflammatory Bowel Disease
- Deaths caused by Fentanyl Overdoses Double in One Year
- Brain Tumours In Men - Diagnostics And Treatments
- All about Adenovirus
- Can Stress Cause Acid Reflux?
- A Popular Prostate Drug Could Lead to Serious Side Effects
- HeartBurn Medicines and Risk of Deaths
- Deep Brain Simulations And Higher Survival Rate For Parkinson's Disease Patients
- A New Treatment Can Relieve Childhood Eczema and Asthma
- Asthma Drug Could Be a Potential Drug for Treating Aortic Aneurysm
- Ankylosing Spondylitis
- Parkinson`S Effect On The Gut
- Hepatitis B
- Optimize Cholesterol Level
- Lump Isn’t Always the First Sign of Breast Cancer
- Calcium And Vitamin D Supplements Do Not Help In Lowering Risk Of Bone Fracture
- A Simple Molecule Can Help in Overcoming Pre-Diabetes
- Bone Repair Process Trigger Through Nanophenomenon
- Blood Sodium Levels Impacts Cognition in Late Adulthood
- Cervical Spondylosis
- Enzyme’s Role in Burning Calories during Dieting and Obesity
- Calcium Pills May Facilitate Artery Build-up
- Benign Fasciculation Syndrome And Causes
- Certain Genes Can Help Bladder Cancer And Its Treatment
- Botox Injections Could Help With Migraine Pain in Children and Adolescents
- Supervised Injection Facilities to Help In Reducing Overdose Deaths
- Study Suggest There is a Role of Vitamin D3 to Heal or Prevent Cardiovascular Injuries
- Virus Ebola
- Antiemetic Drugs - Types and Side Effects
- Drugs To Reduce Harmfully Fat Cells
- Diabetic Foot Ulcers and Its Impact
- Have We Invited Our Suffering?
- According To Scientists, The Flavours Of E-Cigarette Are Toxic To The White Blood Cells
- Birth Control Pills Enhance the Risk of Breast Cancer
- Commonly Used Heartburn Medications Liked to Kidney Trouble
- Better Anti-Thrombotic Medication Target Identified
- Antioxidants Might Not Curb Dementia
- Does Asthma Have A Cure?
- New Drug Could Help In Fighting TB
- How to ease the Side Effects of ADHD Drugs in Adults
- Association Between Five Vascular Diseases And A Common Single Genetic Variant
- Melanoma Survival And Impact Of Existing Drugs
- Home Remedies for Hemorrhoids!
- Atrial Fibrillation
- Prevention of Osteopenia!